| Boost in motivation & energy | Ritalin / Cocaine (mild) | Dopamine | Drive, excitement, "ready to go" feeling |
| Warmth, mood uplift | MDMA (light) | Serotonin | Emotional glow, reduced anxiety, social warmth |
| Calm joy + light euphoria | Alcohol (1-2 drinks level) | Endorphins + GABA | Relaxation, loosened mood, pleasure |
| Pain relief, peaceful high | Morphine / Opioids | Endorphins | Runner's high, physical comfort |
| P Brain clarity, creativity | Microdose LSD / Ketamine | BDNF + Dopamine | Flow, focus, mind expansion |
| Focus, sharp alertness | Adderall / Modafinil | Adrenaline + Norepinephrine | Mental edge, faster thinking |
| Calm, bliss, inner peace | Cannabis (mild THC) | Anandamide | Chill, inner glow, contentment |